The role of intravenous immunoglobulins in the treatment of rheumatoid arthritis.

作者: Nurit Katz-Agranov , Saakshi Khattri , Gisele Zandman-Goddard

DOI: 10.1016/J.AUTREV.2015.04.003

关键词:

摘要: Intravenous immunoglobulins (IVIGs) are beneficial and safe for various diseases other than primary immunodeficiencies. Over the years, IVIG has been given autoimmune as an off-label adjunct therapy. While biologic agents indicated rheumatoid arthritis (RA), may have a role specific subgroups of RA patients where anti-cytokine blockers or rituximab be unwarranted. Such include with vasculitis, overlap rhupus syndrome, severe infections active disease, pregnancy. In addition, considered juvenile chronic (JCA) adult Still's disease. We review literature treatment in these subgroups.

参考文章(123)
Nobunaga M, Malignant rheumatoid arthritis Nihon rinsho. Japanese journal of clinical medicine. ,vol. 50, pp. 597- 602 ,(1992)
Uziel Y, Silverman Ed, Schneider R, Laxer Rm, Intravenous immunoglobulin therapy in systemic onset juvenile rheumatoid arthritis: a followup study. The Journal of Rheumatology. ,vol. 23, pp. 910- 918 ,(1996)
Ballanti E, Perricone R, Perricone C, Novelli L, Di Muzio G, Churg-Strauss syndrome with neurologic manifestations: successful treatment with intravenous immunoglobulins. Israel Medical Association Journal. ,vol. 14, pp. 583- 585 ,(2012)
Maksymowych Wp, Luong M, Aviña-Zubieta A, Russell As, High dose intravenous immunoglobulin (IVIg) in severe refractory rheumatoid arthritis: no evidence for efficacy. Clinical and Experimental Rheumatology. ,vol. 14, pp. 657- 660 ,(1996)
R P Sundel, D J Lovell, B L Tague, E H Giannini, E D Silverman, N Ruperto, Intravenous immunoglobulin in the treatment of polyarticular juvenile rheumatoid arthritis: a phase I/II study. Pediatric Rheumatology Collaborative Study Group. The Journal of Rheumatology. ,vol. 23, pp. 919- 924 ,(1996)
D. J. Lovell, G. D. Cawkwell, E. H. Giannini, T. J. A. Lehman, L. S. Zemel, E. D. Silverman, M. H. Passo, R. M. Laxer, Intravenous immunoglobulin in the treatment of systemic juvenile rheumatoid arthritis: a randomized placebo controlled trial. Pediatric Rheumatology Collaborative Study Group. The Journal of Rheumatology. ,vol. 21, pp. 2353- 2358 ,(1994)
Marissa M Alejandria, Mary Ann D Lansang, Leonila F Dans, Jacinto Blas Mantaring III, Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock Cochrane Database of Systematic Reviews. ,vol. 2013, ,(2013) , 10.1002/14651858.CD001090.PUB2
Michel De Bandt, , Jean Sibilia, Xavier Le Loët, Sebastian Prouzeau, Bruno Fautrel, Christian Marcelli, Eric Boucquillard, Jean Louis Siame, Xavier Mariette, Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: a French national survey Arthritis Research & Therapy. ,vol. 7, pp. 1- 7 ,(2005) , 10.1186/AR1715