MATERNAL ANXIETY DURING PREGNANCY: ITS RELATIONS TO BIRTH OUTCOMES AND TO OFFSPRING DEPRESSION DURING LATE CHILDHOOD AND ADOLESCENCE

摘要: There has been renewed interest in recent years the short- and long-term effects of prenatal maternal anxiety (PMA) on offspring. Although relations between PMA adverse birth outcomes have established previously, nature these is not well-characterized. Furthermore, it unknown whether last into late childhood adolescence to increase offspring’s risk depression. The goals this dissertation were: 1) Characterize outcomes; 2) Determine correlates Major Depressive Disorder (MDD) among offspring; 3) predicts depressive symptoms offspring at 10 16 years. Women (n=829) low socioeconomic status, recruited from a clinic, were assessed for trait during their fourth seventh gestational months, delivery, study substance use. 763 live singleton births. At 10, 14, post-partum, measured women Offspring MDD. Demographic, social, use, medical, psychological, psychiatric status controlled. It was demonstrated first paper that predicted lower weight, shorter length, controlling confounders. who reported chronic, severe highest having gestations delivering smaller babies. second female gender, history maltreatment, MDD independently increased odds 16-year-olds. Daughters with particularly vulnerable. third found related level adolescence. These significant, current Female gender education also children ages 10-16 significant interaction follow-up assessment. findings public health implications: psychological pregnancy throughout child’s development should be monitored order improve adolescents.