Hormonal Modulation of Cytosolic Free Calcium
作者： Peter F. Blackmore
DOI: 10.1016/S0002-9629(15)40864-X
关键词:
摘要: Many hormones are capable of increasing [Ca2+]i in many different tissues by mobilizing Ca2+ from internal stores, primarily the endoplasmic reticulum, and promoting influx across plasma membrane. Recent studies suggest that both processes involve G-proteins. In one case, a G-protein activates PI 4,5-P2 specific phospholipase C, resulting formation Ins 1,4,5-P3, which then releases reticulum. can be stimulated low concentrations agonist, do not promote mobilization. This process appears to directly G-protein.
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