Perspective: Neuroregenerative Nutrition

作者: Brent A Reynolds , Dennis A Steindler , Dennis A Steindler

DOI: 10.3945/AN.117.015388

关键词:

摘要: Good health while aging depends upon optimal cellular and organ functioning that contribute to the regenerative ability of body during lifespan, especially when injuries diseases occur. Although diet may help in maintenance fitness periods stability or modest decline function an organ, this approach is inadequate aged system, which maintain homeostasis further challenged by ensuing suboptimal unit, tissue-specific stem cells. Focused nutritional approaches can be used as intervention reduce body's capacity. This article brings together nutrition-associated therapeutic with fields aging, immunology, neurodegenerative disease, cancer propose ways nutrition work standard-of-care integrated medicine improve brain's it ages. The field has exploded past 2 decades a result discovery cells nearly every system body, including brain, where neural persist discrete areas throughout life. fact, uncovering genetic basis plasticity somatic cells, open door world regeneration systems extend life expectancy beyond its present limits. An area received little attention influence on regulatory mechanisms potential nutrition. We strong relation exists between brain at key times could not only units humans age but also play primary role treatments combat injury (in particular, those occur latter one-third lifespan).

参考文章(127)
Antonio Roma de Vivar Chevez, James Finke, Ronald Bukowski, The role of inflammation in kidney cancer. Advances in Experimental Medicine and Biology. ,vol. 816, pp. 197- 234 ,(2014) , 10.1007/978-3-0348-0837-8_9
Ryan Clanton, David Saucier, John Ford, Gamal Akabani, None, Microbial influences on hormesis, oncogenesis, and therapy: A review of the literature. Environmental Research. ,vol. 142, pp. 239- 256 ,(2015) , 10.1016/J.ENVRES.2015.06.026
Shibu M. Poulose, Nopporn Thangthaeng, Marshall G. Miller, Barbara Shukitt-Hale, Effects of pterostilbene and resveratrol on brain and behavior Neurochemistry International. ,vol. 89, pp. 227- 233 ,(2015) , 10.1016/J.NEUINT.2015.07.017
Juan Sanchez-Ramos, Cynthia Cimino, Ross Avila, Amanda Rowe, Ren Chen, Glenn Whelan, Xiaoyang Lin, Chuanhai Cao, Raj Ashok, Pilot Study of Granulocyte-Colony Stimulating Factor for Treatment of Alzheimer's Disease Journal of Alzheimer's Disease. ,vol. 31, pp. 843- 855 ,(2012) , 10.3233/JAD-2012-120196
K.R. Magnusson, L. Hauck, B.M. Jeffrey, V. Elias, A. Humphrey, R. Nath, A. Perrone, L.E. Bermudez, Relationships Between Diet-Related Changes in the Gut Microbiome and Cognitive Flexibility Neuroscience. ,vol. 300, pp. 128- 140 ,(2015) , 10.1016/J.NEUROSCIENCE.2015.05.016
Antoine Louveau, Igor Smirnov, Timothy J. Keyes, Jacob D. Eccles, Sherin J. Rouhani, J. David Peske, Noel C. Derecki, David Castle, James W. Mandell, Kevin S. Lee, Tajie H. Harris, Jonathan Kipnis, Structural and functional features of central nervous system lymphatic vessels Nature. ,vol. 523, pp. 337- 341 ,(2015) , 10.1038/NATURE14432
Emanuele-Salvatore Scarpa, Paolino Ninfali, Phytochemicals as Innovative Therapeutic Tools against Cancer Stem Cells International Journal of Molecular Sciences. ,vol. 16, pp. 15727- 15742 ,(2015) , 10.3390/IJMS160715727
Isabella Russo, Sergio Barlati, Francesca Bosetti, Effects of neuroinflammation on the regenerative capacity of brain stem cells. Journal of Neurochemistry. ,vol. 116, pp. 947- 956 ,(2011) , 10.1111/J.1471-4159.2010.07168.X
Judith Schwartzbaum, Michal Seweryn, Christopher Holloman, Randall Harris, Samuel K. Handelman, Grzegorz A. Rempala, Ruo-Pan Huang, Brett Burkholder, Adam Brandemihl, Henrik Kallberg, Tom Borge Johannesen, Anders Ahlbom, Maria Feychting, Tom K. Grimsrud, Association between Prediagnostic Allergy-Related Serum Cytokines and Glioma PLOS ONE. ,vol. 10, pp. e0137503- ,(2015) , 10.1371/JOURNAL.PONE.0137503