Synthesis of β- and β,β-substituted Morita-Baylis- Hillman adducts using a two-step protocol
作者： David I. Magee , Same Ratshonka , Jessica McConaghy , Maggie Hood
DOI: 10.1139/V2012-017
关键词:
摘要: The synthesis of a large number β- and β,β-substituted keto esters was successful by the use Knoevenagel condensation reaction. stereoselectivity these reactions improved al...
elsevier.com
nrcresearchpress.com参考文章(54)
Fides Benfatti, Giuliana Cardillo, Luca Gentilucci, Elisa Mosconi, Alessandra Tolomelli, Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates. Organic Letters. ,vol. 10, pp. 2425- 2428 ,(2008) , 10.1021/OL8006919
Bruce D. Roth, C. J. Blankley, A. W. Chucholowski, E. Ferguson, M. L. Hoefle, D. F. Ortwine, R. S. Newton, C. S. Sekerke, D. R. Sliskovic, M Wilson, Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran 2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus Journal of Medicinal Chemistry. ,vol. 34, pp. 357- 366 ,(1991) , 10.1021/JM00105A056
Rikuhei Tanikaga, Naoto Konya, Kazumasa Hamamura, Aritsune Kaji, Stereochemical Behavior of Intermediary Compounds in the Amine-Catalyzed Knoevenagel Reaction Bulletin of the Chemical Society of Japan. ,vol. 61, pp. 3211- 3216 ,(1988) , 10.1246/BCSJ.61.3211
Giuliana Cardillo, Arianna Gennari, Luca Gentilucci, Elisa Mosconi, Alessandra Tolomelli, Stefano Troisi, Dehydro‐β‐amino Acid Containing Peptides as Promising Sequences for Drug Development European Journal of Organic Chemistry. ,vol. 2009, pp. 5991- 5997 ,(2009) , 10.1002/EJOC.200900870
Duncan A. R. Happer, Bruce E. Steenson, Preparation of α,β-Unsaturated Sulfones by the Knoevenagel Method Synthesis. ,vol. 1980, pp. 806- 807 ,(1980) , 10.1055/S-1980-29213
Joseph Paul Marino, Russell J. Linderman, Chemistry of substituted [.alpha.-(carboethoxy)vinyl]cuprates and their synthetic application to cyclopentenone annulations Journal of Organic Chemistry. ,vol. 13, pp. 3696- 3702 ,(1981) , 10.1021/JO00331A023
Tsuneo Imamoto, Tetsuo Kusumoto, Yoshinori Tawarayama, Yasushi Sugiura, Takeshi Mita, Yasuo Hatanaka, Masataka Yokoyama, Carbon-carbon bond-forming reactions using cerium metal or organocerium(III) reagents Journal of Organic Chemistry. ,vol. 49, pp. 3904- 3912 ,(1984) , 10.1021/JO00195A006
Fides Benfatti, Giuliana Cardillo, Luca Gentilucci, Elisa Mosconi, Alessandra Tolomelli, Enzymatic resolution of ethyl 3-hydroxy-2(1′substituted-methylidene)-butyrate by Pseudomonas cepacia lipase catalyzed acetylation Tetrahedron-asymmetry. ,vol. 18, pp. 2227- 2232 ,(2007) , 10.1016/J.TETASY.2007.09.002
Jacob Zabicky, 137. The kinetics and mechanism of carbonyl–methylene condensation reactions. Part XI. Stereochemistry of the products J. Chem. Soc.. ,vol. 0, pp. 683- 687 ,(1961) , 10.1039/JR9610000683
Roberto Antonioletti, Paolo Bovicelli, Savina Malancona, A new route to 2-alkenyl-1,3-dicarbonyl compounds, intermediates in the synthesis of dihydrofurans Tetrahedron. ,vol. 58, pp. 589- 596 ,(2002) , 10.1016/S0040-4020(01)01173-5