Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r)
作者： Kris Reedquist , Kevin Baker , Brian Wong , Emma Masteller , Julie Hambleton
DOI:
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摘要: Methods of reducing cytokine levels and methods treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R) are provided. Such include, but not limited to, inflammatory conditions, such as rheumatoid arthritis.
lens.org参考文章(140)
Elaine Y. Lin, Valerie Gouon-Evans, Andrew V. Nguyen, Jeffrey W. Pollard, The macrophage growth factor CSF-1 in mammary gland development and tumor progression. Journal of Mammary Gland Biology and Neoplasia. ,vol. 7, pp. 147- 162 ,(2002) , 10.1023/A:1020399802795
MN Saleh, SJ Goldman, AF LoBuglio, AC Beall, H Sabio, MC McCord, L Minasian, RK Alpaugh, LM Weiner, DH Munn, CD16+ monocytes in patients with cancer: spontaneous elevation and pharmacologic induction by recombinant human macrophage colony- stimulating factor Blood. ,vol. 85, pp. 2910- 2917 ,(1995) , 10.1182/BLOOD.V85.10.2910.BLOODJOURNAL85102910
Jeffrey Nemeth, Method of Using IL6 Antagonists with Mitoxantrone for Prostate Cancer ,(2007)
Kirston Koths, William Michael Kavanaugh, Cheng Liu, Li Long, Deborah Lee Zimmerman, Gregory Martin Harrowe, M-csf muteins and uses thereof ,(2005)
Roberto Polakiewicz, Valerie Goss, Ting-Lei Gu, Denise Walters, Brian Druker, Translocation and mutant CSF1R Kinase in human leukemia ,(2008)
Justin Wong, Maximiliano Vasquez, Antibodies that bind csf1r ,(2011)
Kirston Koths, Anna Lisa Fear, Sung-Hou Kim, Ralph Yamamoto, Andrew Bohm, Eric Taylor, Jarmila Jancarik, Jayvardhan Pandit, Robert Halenbeck, Crystallization of M-CSF.alpha. ,(1999)
T. van Daalen Wetters, S.A. Hawkins, M.F. Roussel, C.J. Sherr, Random mutagenesis of CSF-1 receptor (FMS) reveals multiple sites for activating mutations within the extracellular domain. The EMBO Journal. ,vol. 11, pp. 551- 557 ,(1992) , 10.1002/J.1460-2075.1992.TB05086.X
Stefan Dübel, Janice M Reichert, Handbook of therapeutic antibodies Wiley Blackwell,. pp. 1- 4 ,(2007) , 10.1002/9783527619740
Haishan Lin, Li Long, Csf1r extracellular domain fusion molecules and treatments using same ,(2009)