Diagnosing Keratoconus Using VHF Digital Ultrasound Epithelial Thickness Profiles

摘要: There have been significant advances in keratoconus screening over the past decade largely due to enhanced analysis of corneal tomography; however, there remain some equivocal cases where a confident diagnosis cannot be made. Epithelial thickness mapping provides adjunctive diagnostic information that can help confirm or exclude suspicious cases. The epithelium has ability alter its profile re-establish smooth, symmetrical optical outer surface and either partially totally mask stromal irregularities from front topography. In keratoconus, this manifests as epithelial thinning cone surrounded by an annulus thickening, increasing thickening with disease progression. early remodelling enough completely cone, resulting apparently normal This explain reports “ectasia without cause”. eye eccentric back apex, coincident doughnut pattern would whereas lack localized keratoconus. Very high-frequency digital ultrasound provide maps for 10 mm diameter, OCT do up 9 diameter. A number groups are now working on developing automated algorithms screen based encouraging results.