Effects of simultaneous bilateral tDCS of the human motor cortex.

摘要: Background Transcranial direct current stimulation (tDCS) is a noninvasive technique that has been investigated as therapeutic tool for different neurologic disorders. Neuronal excitability can be modified by application of DC in polarity-specific manner: anodal tDCS increases excitability, while cathodal decreases excitability. Previous research shown simultaneous bilateral the human motor cortex facilitates performance stimulated hemisphere much more than when same using unilateral tDCS. Objective The main purpose this study was to determine whether able increase cortical one whereas decreasing contralateral hemisphere. To test our hypothesis, before and after evaluated. Moreover, effects were compared with those Methods We evaluated healthy volunteers or transcranial magnetic stimulation. Results demonstrated over induces an on anodal-stimulated side decrease side. also used electrode montage (motor cortex-contralateral orbit) method compare montage. induced similar cathode-stimulated On side, seems slightly less robust arrangement placement electrodes orbit found intersubject variability changes lower Conclusions This first which extensively evaluated, Simultaneous useful obtain causing (e.g.,to treat stroke).