作者: Matthew A. Allison , Mary Cushman , Cam Solomon , Victor Aboyans , Mary M. McDermott
DOI: 10.1016/J.JVS.2009.05.061
关键词:
摘要: Background The aim of this study was to determine the risk factors for conversion from a normal either low or high ankle-brachial index (ABI). Methods Participants in Multi-Ethnic Study Atherosclerosis who had two separate measurements ABI over 3-year time period were assessed. Results At baseline, mean age 62 years and 50% women, 28% African American, 12% Chinese, 22% Hispanic 38% non-Hispanic White. Of 5514 participants with baseline between 0.90 1.40, 89 (1.6%) an ≤ ("low group") 71 (1.3%) ≥ 1.40 ("high 3 later. On multivariable analysis, odds having progressed into group significantly increased higher age, hypertension, diabetes, greater pack-years cigarette smoking, homocysteine levels. progression male gender body mass index. Compared Whites, Americans (odds ratio [OR]: 2.24, 95% confidence interval [CI]: 1.29-3.88) while reduced (OR: 0.50, CI: 0.24-1.00). Neither Chinese nor ethnicity associated group. Conclusions distinct at but decreased