Therapeutic uses for Angiotensin-(1-7).

作者: Alice Machado-Silva , Danielle Passos-Silva , Robson Augusto Santos , Rubén Dario Sinisterra

DOI: 10.1080/13543776.2016.1179283

关键词:

摘要: ABSTRACTIntroduction: Angiotensin-(1-7) is a key component of the Renin-Angiotensin System, which can counter-regulate several deleterious effects caused by angiotensin II. Due to potential for therapeutic use, its actions are specifically described in patents.Areas covered: In this review, authors describe plethora uses Angiotensin-(1-7), claimed and supported experimental evidence patent documents applications.Expert opinion: The clinical as agent treat pathologies evidenced variety patents trials involving peptide. Cancer treatment one most advanced areas, but studies also available other such cardiovascular, hematological, transplantation, surgical medical procedures.

参考文章(78)
西赫尔·阿德里安·内勒曼斯, 劳沃·德弗里斯, 安东尼厄斯·雅各布斯·马里努斯·罗克斯, 赫特·尼古拉斯·摩尔, 里克·林克, Novel angiotensin type 2 (at2) receptor agonists and uses thereof ,(2011)
Mohan K Raizada, André Augusto Gomes Faraco, Danielle Carvalho De Oliveira Coutinho, Juçara Ribeiro Franca, Gustavo De Oliveira Fulgêncio, José Carlos Nogueira, Bárbara Silva Nogueira, Giselle Foureaux De Faria, Anderson José Ferreira, Robson Augusto Souza Dos Santos, Pharmaceutical compositions containing angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis activators for the treatment of ocular pathological conditions ,(2013)
Anita Driessen-Levels, Edze Jan Tijsma, Angiotensin (1-7) eluting stent ,(2007)
W. Nemoto, Y. Ogata, O. Nakagawasai, F. Yaoita, T. Tadano, K. Tan-No, Angiotensin (1–7) prevents angiotensin II-induced nociceptive behaviour via inhibition of p38 MAPK phosphorylation mediated through spinal Mas receptors in mice European Journal of Pain. ,vol. 18, pp. 1471- 1479 ,(2014) , 10.1002/EJP.512
Rodrigo A. Fraga‐Silva, Fabiana P. Costa‐Fraga, Silvia Q. Savergnini, Frederico B. De Sousa, Fabrizio Montecucco, Daniele da Silva, Ruben D. Sinisterra, François Mach, Nikolaos Stergiopulos, Rafaela F. da Silva, Robson A.S. Santos, An oral formulation of angiotensin-(1-7) reverses corpus cavernosum damages induced by hypercholesterolemia. The Journal of Sexual Medicine. ,vol. 10, pp. 2430- 2442 ,(2013) , 10.1111/JSM.12262
Elizabeth A. Novak, Kevin P. Mollen, Mitochondrial dysfunction in inflammatory bowel disease. Frontiers in Cell and Developmental Biology. ,vol. 3, pp. 62- 62 ,(2015) , 10.3389/FCELL.2015.00062
Gesmar Volga Haddad Herdy, Roberta Duarte Bezerra Pinto, Guilherme de Almeida Costa, Ana Flavia Malheiros Torbey, Vivianne Galante Ramos, Marcio Moacyr Vasconcelos, Clinical and Molecular Study on Duchenne Muscular Dystrophy International Journal of Cardiovascular Sciences. ,vol. 28, pp. 173- 180 ,(2015) , 10.5935/2359-4802.20150026