作者: Charing Ching Ning Chong , Anthony Yuen Bun Teoh , Raymond Shing Yan Tang , Anthony Wing Hung Chan , Enders Kwok Wai Ng
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摘要: Objectives: The project is aimed to compare the tissue sampling rate and diagnostic accuracy of EUS-FNA using 22G nitinol reverse bevel-tipped needles. Subjects Methods: This was a prospective, randomized, crossover study in tertiary academic hospital. All consecutive adult patients undergoing EUS-guided FNA for lesions > 2 cm were recruited. Patients fulfilling inclusion exclusion criteria underwent both needles sequence. They randomized on 1:1 basis determine whether would be performed first (ProCore) needle followed by or vice versa. pathologists blinded type used. Results: Forty with suspected malignant neoplasms recruited study. No significant differences found yield (76.9% vs. 84.6%, P = 0.389), (71.8% 0.170), sensitivity (77.8% 86.1%, 0.358), specificity (100% 100%, 1), positive predictive value negative (20.0% 28.6%, 1). percentage obtained histological assessment also similar (41.0% 46.2%, 0.648). In terms quantity needles, larger proportion group more (P 0.003). Conclusion: tissue-sampling new ProCore comparable conventional absence an on-site cytopathologist.