Functional innervation of the adrenal cortex by the splanchnic nerve.

摘要: Secretion of steroid hormones by the adrenal cortex is required to maintain whole body homeostasis; that ability blood pressure and volume, carbohydrate, protein fat metabolism immune nervous system function within normal limits dependent on adrenocortical hormones. The premise this report autonomic-endocrine interactions occurring in are for control secretion. Under non-stress conditions when reduced secretion required, splanchnic neural activity appears be inhibitory, whereas during stress elevated necessary, excitatory. capacity innervation produce both inhibitory excitatory effects suggests input must encoded differentially; encoding could neurotransmitter released or intra-adrenal target affected. Neural act directly at cell affect steroidogenesis indirectly changing flow. An index role has been obtained assessing corticosteroid after splanchnicectomy, severing thoracic nerve which major source gland. This approach resulted alterations under conditions, but many cases demonstrated no profound effect vivo steroidogenesis. It likely splanchnicectomy results variable secretory responses part due multiplicity systems regulated nerve. Splanchnicectomy alters multiple neurotransmitters different sites. Splanchnic acts as an extra-ACTH mechanism secretion, yet further elucidation physiological affects clearly warranted.