Rearrangements of the transposable mating-type cassettes of fission yeast.

摘要: The fission yeast, Schizosaccharomyces pombe, switches mating type every few cell divisions. Switching is controlled by the genes of mating-type locus, which consists three components, mat1, mat2-P and mat3-M, each separated approximately 15 kb. Copy transposition P (Plus) or M (Minus) information from mat3-M into expression locus mat1 mediates switching. undergoes events at high frequency (10(-2)-10(-6)) stabilize one other type. These are shown to be rearrangements result in either deletion insertion DNA between cassettes.