Gradients in the in vivo intestinal stem cell compartment and their in vitro recapitulation in mimetic platforms.

作者: David Newport , Sinead Connolly , Sigita Malijauskaite , Kieran McGourty

DOI: 10.1016/J.CYTOGFR.2021.03.002

关键词:

摘要: Intestinal tissue, and specifically its mucosal layer, is a complex and gradient-rich environment. Gradients of soluble factor (BMP, Noggin, Notch, Hedgehog, and Wnt) …

参考文章(147)
Rafael Gomez-Sjoberg, Anne A. Leyrat, Benjamin T. Houseman, Kevan Shokat, Stephen R. Quake, Biocompatibility and reduced drug absorption of sol-gel-treated poly(dimethyl siloxane) for microfluidic cell culture applications. Analytical Chemistry. ,vol. 82, pp. 8954- 8960 ,(2010) , 10.1021/AC101870S
Hiutung Chu, Sarkis K Mazmanian, Innate immune recognition of the microbiota promotes host-microbial symbiosis Nature Immunology. ,vol. 14, pp. 668- 675 ,(2013) , 10.1038/NI.2635
Toshiro Sato, Robert G. Vries, Hugo J. Snippert, Marc van de Wetering, Nick Barker, Daniel E. Stange, Johan H. van Es, Arie Abo, Pekka Kujala, Peter J. Peters, Hans Clevers, Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche Nature. ,vol. 459, pp. 262- 265 ,(2009) , 10.1038/NATURE07935
A. Quaroni, K. J. Isselbacher, E. Ruoslahti, Fibronectin synthesis by epithelial crypt cells of rat small intestine Proceedings of the National Academy of Sciences of the United States of America. ,vol. 75, pp. 5548- 5552 ,(1978) , 10.1073/PNAS.75.11.5548
Yukimasa Taniguchi, Hiroyuki Ido, Noriko Sanzen, Maria Hayashi, Ryoko Sato-Nishiuchi, Sugiko Futaki, Kiyotoshi Sekiguchi, The C-terminal Region of Laminin β Chains Modulates the Integrin Binding Affinities of Laminins Journal of Biological Chemistry. ,vol. 284, pp. 7820- 7831 ,(2009) , 10.1074/JBC.M809332200
Kyung-Jin Jang, Ali Poyan Mehr, Geraldine A. Hamilton, Lori A. McPartlin, Seyoon Chung, Kahp-Yang Suh, Donald E. Ingber, Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integrative Biology. ,vol. 5, pp. 1119- 1129 ,(2013) , 10.1039/C3IB40049B
Xianmin Meng, John F. Klement, Dominic A. Leperi, David E. Birk, Takako Sasaki, Rupert Timpl, Jouni Uitto, Leena Pulkkinen, Targeted inactivation of murine laminin γ2-chain gene recapitulates human junctional epidermolysis bullosa Journal of Investigative Dermatology. ,vol. 121, pp. 720- 731 ,(2003) , 10.1046/J.1523-1747.2003.12515.X
Joan E. Kuster, Mary H. Guarnieri, Jeffrey G. Ault, Lorraine Flaherty, Pamela J. Swiatek, IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa. Mammalian Genome. ,vol. 8, pp. 673- 681 ,(1997) , 10.1007/S003359900535
Hyun Jung Kim, Donald E. Ingber, Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation Integrative Biology. ,vol. 5, pp. 1130- 1140 ,(2013) , 10.1039/C3IB40126J