Cytologic diagnosis of adenoid cystic carcinoma of salivary glands

作者: Holger Nagel , Hermann Josef Hotze , Rainer Laskawi , Reinhard Chilla , Manfred Droese

DOI: 10.1002/(SICI)1097-0339(199906)20:6<358::AID-DC6>3.0.CO;2-X

关键词:

摘要: The cytomorphologic features in fine-needle aspiration (FNA) biopsies from 31 primary and 33 recurrent adenoid cystic carcinomas (ACC) were investigated. correct FNA diagnosis was established 24 of ACC (77%). diagnostic clue aspirates are large globules extracellular matrix, partially surrounded by basaloid tumor cells. In FNAs with predominance cells, but lacking characteristic globules, all other benign malignant salivary gland tumors epithelial-myoepithelial differentiation should be considered the cytologic diagnosis. Pleomorphic adenoma is most frequently confused ACC, therefore, findings 50 pleomorphic adenomas compared those diagnosed as ACC. Furthermore, rare neoplasms glands cell differentiation, including basal-cell carcinoma, polymorphous low-grade adenocarcinoma, well some nonsalivary presenting an pattern, must considered. these entities discussed detail respect to criteria

参考文章(39)
M.M. Abad, C. G-Macias, M.J. Alonso, E. Munoz, J.I. Paz, P. Galindo, A. Herrero, A. Bullon, Statistical evaluation of the predictive power of fine needle aspiration (FNA) of salivary glands. Results and cytohistological correlation. Pathology Research and Practice. ,vol. 188, pp. 340- 343 ,(1992) , 10.1016/S0344-0338(11)81214-8
John D. Casler, John J. Conley, Surgical management of adenoid cystic carcinoma in the parotid gland. Otolaryngology-Head and Neck Surgery. ,vol. 106, pp. 332- 338 ,(1992) , 10.1177/019459989210600403
B J Glasgow, L J Layfield, P Tan, Fine-needle aspiration of salivary gland lesions. Comparison with frozen sections and histologic findings. Archives of Pathology & Laboratory Medicine. ,vol. 111, pp. 346- 353 ,(1987)
Steven D. Vincent, Harold L. Hammond, Michael W. Finkelstein, Clinical and therapeutic features of polymorphous low-grade adenocarcinoma Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 77, pp. 41- 47 ,(1994) , 10.1016/S0030-4220(06)80105-2
Douglas R. Gnepp, Ju Cheng Chen, Cindy Warren, Polymorphous low-grade adenocarcinoma of minor salivary gland. An immunohistochemical and clinicopathologic study. The American Journal of Surgical Pathology. ,vol. 12, pp. 461- 468 ,(1988) , 10.1097/00000478-198806000-00006
Michael W. Stanley, Charles A. Horwitz, Michelle J. Henry, Linda G. Burton, Torsten Lowhagen, Basal‐cell adenoma of the salivary gland: A benign adenoma that cytologically mimics adenoid cystic carcinoma Diagnostic Cytopathology. ,vol. 4, pp. 342- 346 ,(1988) , 10.1002/DC.2840040414
Timothy F. Kolda, Thuy-Dung T. Ardaman, Mary R. Schwartz, Eccrine Spiradenoma Mimicking Adenoid Cystic Carcinoma on Fine Needle Aspiration Acta Cytologica. ,vol. 41, pp. 852- 858 ,(1997) , 10.1159/000332716