An isoform‐specific PDZ‐binding motif targets type I PIP5 kinase beta to the uropod and controls polarization of neutrophil‐like HL60 cells

作者: Santos Mañes , Gloria Fuentes , Rosa M. Peregil , Ana M. Rojas , Rosa Ana Lacalle

DOI: 10.1096/FJ.09-153106

关键词:

摘要: Type I phosphatidylinositol 4-phosphate 5-kinase (PIP5KI)-β participates in establishing polarity during leukocyte chemotaxis. Its final 83 amino acids localize PIP5KIβ to the uropod of chemotaxing...

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