作者: M Migliori , P Tomassetti , D Campana , S Boschi , R Pezzilli
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摘要: Background: The diagnostic value of the determination serum pancreatic polypeptide (PP) and gastrin concentrations after a standard meal for early diagnosis patients with multiple endocrine neoplasia type 1 (MEN 1) is controversial. aim this study was to clarify issue. Thirteen MEN 1, seven healthy family members, eight controls were studied. Plasma PP measured before ingestion standardized meal. caused statistically significant (p<0.05) increase both in all three groups Concerning PP, no difference observed between controls. In values significantly lower than other two groups. On whole, differences levels noted controls; patients. All who had abnormally high postprandial also basal these peptides. stimulation test adds information about presence tumors over that provided by