Purposive-Rational Tumor Therapy: Exploiting the Tumor’s ‘Living World’ for Diversifying, Specifying and Personalizing Tumor Therapy
作者： Albrecht Reichle , Gerhard C Hildebrandt , None
DOI: 10.1007/978-94-007-6866-6_15
关键词:
摘要: Evolution-adjusted tumor pathophysiology introduces the view of systems participators to assess evolutionarily constrained validities and denotations participators, contrasts with manacle classic disciplines, pathology pathophysiology, which provide observers. The differential perspective communicative interaction applied by an evolution-adjusted (1) involves comprehension tumor’s features at diagnosis accentuating aspects a situation’s analysis, (2) allows situating identity function as subjects during therapies modulating communication, (3) facilitates describe ‘living world’ comprising (all) endogenously or therapeutically redeemable validity claims objects, (4) contributes select specify purposive therapy pragmatically configure modulate available evolutionary based rationalization processes normative notions (theranostics), (5) affects technologies interfere communication pathologies in (adaptive trial designs). provides contently methodologically novel approaches succeed personalizing therapy, should be introduced clinically orientated discipline, equivalent traditional thereby increasing their value accomplishing ethical demands. A type-specific, stage-specific, metastatic site-specific disease trait-orientated seems within grasp.
springer.com
sci-hub.st 参考文章(64)
Albrecht Reichle, Gerhard C. Hildebrandt, From Molecular to Modular, from Theme-Dependent to Evolution-Adjusted Tumor Therapy Springer, Dordrecht. pp. 545- 556 ,(2010) , 10.1007/978-90-481-9531-2_27
Albrecht Reichle, Gerhard C. Hildebrandt, The Comparative Uncovering of Tumor Systems Biology by Modularly Targeting Tumor-Associated Inflammation Springer, Dordrecht. pp. 287- 303 ,(2010) , 10.1007/978-90-481-9531-2_13
Albrecht Reichle, Gerhard C. Hildebrandt, To Be an Object in a Biological System Springer, Dordrecht. pp. 537- 544 ,(2010) , 10.1007/978-90-481-9531-2_26
Verena Paulitschke, Rainer Kunstfeld, Christopher Gerner, Secretome Proteomics, a Novel Tool for Biomarkers Discovery and for Guiding Biomodulatory Therapy Approaches Springer, Dordrecht. pp. 405- 431 ,(2010) , 10.1007/978-90-481-9531-2_21
Urban Emmenegger, Annabelle Chow, Guido Bocci, The Biomodulatory Capacities of Low-Dose Metronomic Chemotherapy: Complex Modulation of the Tumor Microenvironment Springer, Dordrecht. pp. 243- 262 ,(2010) , 10.1007/978-90-481-9531-2_11
Annika Bundscherer, Christian Hafner, Breathing New Life into Old Drugs: Indication Discovery by Systems Directed Therapy Springer, Dordrecht. pp. 483- 503 ,(2010) , 10.1007/978-90-481-9531-2_24
Yongliang Yang, S. James Adelstein, Amin I. Kassis, Integrated bioinformatics analysis for cancer target identification. Methods of Molecular Biology. ,vol. 719, pp. 527- 545 ,(2011) , 10.1007/978-1-61779-027-0_25
Albrecht Reichle, Uncovering Tumor Systems Biology by Biomodulatory Therapy Strategies Springer, Dordrecht. pp. 469- 481 ,(2010) , 10.1007/978-90-481-9531-2_23
Albrecht Reichle, Bridging Theory and Therapeutic Practice: From Generalized Disease Models to Particular Patients Springer, Dordrecht. pp. 3- 7 ,(2010) , 10.1007/978-90-481-9531-2_1
Fabian Kiessling, Wiltrud Lederle, Early Detection of Systems Response: Molecular and Functional Imaging of Angiogenesis Springer, Dordrecht. pp. 385- 403 ,(2010) , 10.1007/978-90-481-9531-2_20