Effect of Temperature on the Phase Behaviour of Fully Saturated DAPC Lipid Bilayer: A Comparative Molecular Dynamics Simulation Study
作者： Ipsita Basu , Chaitali Mukhopadhyay
DOI: 10.1007/978-3-319-11280-0_17
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摘要: The plasma membrane is made of phospholipid bilayer in which proteins are embedded. physiochemical properties the cell determinant many important cellular processes. lipid has a fluid like consistency and fundamental structure dynamic dependent upon temperature. Depending temperature phases namely gel phase (Lβ), liquid-crystalline (Lα), subgel (Lc), ripple (Pβ). We have investigated structural DAPC at two different temperatures, one above transition (at 350 K) another below (300 K). been able to discriminate temperatures determine behavior lipid. found that change may serious consequences for systems. reduced area per corresponding ordering acyl chain lead bilayer. Energy calculation also supports system 300 K phase. Preliminary studies quantities diffusion coefficient showed this parameter sensitive shows lower value indicating
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