Role of Neurotransmitters in the Genesis of Epileptiform Discharges

摘要: The risk of excessive, runaway activity is probably inherent in the structure cerebral cortex. Vast numbers tightly packed, excitable cells—which can readily interact by releasing K+, generating electrical fields and via direct or indirect excitatory synaptic paths—would inevitably undergo uncontrolled, paroxysmal depolarization firing if indiscriminate excitation was not constantly opposed very potent control mechanisms. remarkable ability normal cortex to function for many years without any signs major uncontrolled irrefutable evidence an astonishingly effective regulation firing.