Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection

摘要: The present invention provides recombinant raccoon poxviruses (RRPVs) useful in vaccines for the prophylaxis of disease caused by feline immunodeficiency virus (FIV). RRPVs according to have at least one internal gene comprising a DNA sequence that encodes FIV gag protein (gag), enveloppe (env), polypeptide consisting amino acids 1-735 env, or immunogenic fragments any foregoing. comprise more FIV-expressing described above may also pharmaceutically acceptable carrier diluent and adjuvant. methods preventing lessening FIV, which is carried out administering need such treatment above.