Nargenicin compounds and uses thereof as antibacterial agents
作者： James M. Apgar , Qun Dang , Dann Parker , Ronald E. Painter , Sheo B. Singh
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摘要: The present invention relates to novel nargenicin related compounds which can inhibit DnaE and have antibacterial, particularly antimycobacterial activity against Mycobacterium tuberculosis. also method for inhibiting growth of mycobacterial cells as well a treating infections by tuberculosis administering an antimycobacterially effective amount or nargenicin-related compound and/or their pharmaceutically acceptable salts.
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