The association between fatty acid index and in vitro fertilization outcomes.

作者: Ashley M. Eskew , Kelly C. Wormer , Michelle L. Matthews , H. James Norton , Margaret A. Papadakis

DOI: 10.1007/S10815-017-1032-1

关键词:

摘要: Fatty acids have been shown to play an important role in oocyte competence and early implantation of the embryo. Our hypothesis-generating study sought determine if individual fatty expressed as a percentage total erythrocyte are associated with embryo quality other vitro fertilization (IVF) outcomes. This was prospective cohort at academic fertility center. Sixty women undergoing their first IVF cycle were recruited. Serum measurements 22 obtained. We calculated each acid acids, defined index for that acid. Omega-3 had no correlation A negative found between trans index, elaidic (EA), outcomes, including rate (r = − 0.261, p = 0.04), blastocyst conversion (r = − 0.41, p = 0.001), number usable blastocysts embryos (r = − 0.411, p = 0.001). There EA oocytes retrieved, grade, or clinical pregnancy. No consistent correlations observed additional analyzed. omega-3 Elevated major commonly consumed hydrogenated oils, margarine, fried foods, negatively correlated embryos, conversion, rate. findings suggest preliminary evidence fat may be

参考文章(31)
K Murakami, S Y Chan, A Routtenberg, Protein kinase C activation by cis-fatty acid in the absence of Ca2+ and phospholipids. Journal of Biological Chemistry. ,vol. 261, pp. 15424- 15429 ,(1986) , 10.1016/S0021-9258(18)66728-6
Janine Hartweg, Rafael Perera, Victor M Montori, Sean F Dinneen, Andrew HAWN Neil, Andrew J Farmer, Omega-3 polyunsaturated fatty acids (PUFA) for type 2 diabetes mellitus. Cochrane Database of Systematic Reviews. ,(2008) , 10.1002/14651858.CD003205.PUB2
M. Arvizu, C. Tanrikut, R. Hauser, M. Keller, J.E. Chavarro, Male dietary trans fat intake is inversely associated to fertilization rates Fertility and Sterility. ,vol. 104, ,(2015) , 10.1016/J.FERTNSTERT.2015.07.320
Lee Hooper, Roger A Harrison, Carolyn D Summerbell, Helen Moore, Helen V Worthington, Andrew Ness, Nigel Capps, George Davey Smith, Rudolph Riemersma, Shah Ebrahim, None, Omega 3 fatty acids for prevention and treatment of cardiovascular disease Cochrane Database of Systematic Reviews. ,(2004) , 10.1002/14651858.CD003177.PUB2
Dariush Mozaffarian, Tobias Pischon, Susan E Hankinson, Nader Rifai, Kaumudi Joshipura, Walter C Willett, Eric B Rimm, None, Dietary intake of trans fatty acids and systemic inflammation in women The American Journal of Clinical Nutrition. ,vol. 79, pp. 606- 612 ,(2004) , 10.1093/AJCN/79.4.606
Jorge Salmerón, Frank B Hu, JoAnn E Manson, Meir J Stampfer, Graham A Colditz, Eric B Rimm, Walter C Willett, Dietary fat intake and risk of type 2 diabetes in women The American Journal of Clinical Nutrition. ,vol. 73, pp. 1019- 1026 ,(2001) , 10.1093/AJCN/73.6.1019
Jorge E. Chavarro, Jeremy Furtado, Thomas L. Toth, Jennifer Ford, Myra Keller, Hannia Campos, Russ Hauser, Trans–fatty acid levels in sperm are associated with sperm concentration among men from an infertility clinic Fertility and Sterility. ,vol. 95, pp. 1794- 1797 ,(2011) , 10.1016/J.FERTNSTERT.2010.10.039
Cadence E. Minge, Rebecca L. Robker, Robert J. Norman, PPAR Gamma: Coordinating Metabolic and Immune Contributions to Female Fertility Ppar Research. ,vol. 2008, pp. 243791- 243791 ,(2008) , 10.1155/2008/243791
Errol R. Norwitz, Danny J. Schust, Susan J. Fisher, Implantation and the survival of early pregnancy. The New England Journal of Medicine. ,vol. 345, pp. 1400- 1408 ,(2001) , 10.1056/NEJMRA000763
Emily S. Jungheim, George A. Macones, Randall R. Odem, Bruce W. Patterson, Susan E. Lanzendorf, Valerie S. Ratts, Kelle H. Moley, Associations between free fatty acids, cumulus oocyte complex morphology and ovarian function during in vitro fertilization Fertility and Sterility. ,vol. 95, pp. 1970- 1974 ,(2011) , 10.1016/J.FERTNSTERT.2011.01.154