作者: Kenneth B. Campbell , Brenda M. Lowick
DOI: 10.1016/0741-8329(87)90021-8
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摘要: A modified auditory "oddball" task was employed to determine the effects of ethanol on event-related potentials (ERPs). Ten subjects ingested either a 0.0 or 1.0 ml/kg dosage 94% counterbalanced days. During each set pre- and post-drug days, heard frequently occurring 1000 Hz standard presented left ear, an infrequently 2000 target distractor right ear. The intensity varied in different conditions. Ethanol ingestion had significant effect number ERP components. amplitudes vertex N1b P2 were significantly attenuated suggesting that ethanol's influence is probably due more depressive operating at level sensation than decrease subject's state attentiveness. P3 found be reduced amplitude but only following not target, possibly reflecting interaction difficulty informational value stimulus. There little evidence greater susceptibility hemisphere compared association areas cortex.