Enzymatic Hydrolysis of the α-Protein of Epidermis *

作者: Howard P. Baden

DOI: 10.1111/1523-1747.EP12280687

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摘要: Treatment of the highly aggregated S-carboxymethyl derivative α-protein epidermis with trypsin or chymotrypsin results in progressive hydrolysis to small peptides no helical structure. However, experiments done at 4°C enzyme-to-protein ratios 1/1000 for short periods time resulted formation three distinct components varying size. X-ray diffraction and amino acid analyses protein from indicate that breaks down into fragments non-helical

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