Sp1 elements protect a CpG island from de novo methylation
作者： Michael Brandeis , Dale Frank , Iiana Keshet , Zahava Siegfried , Monica Mendelsohn
DOI: 10.1038/371435A0
关键词:
摘要: ANIMAL somatic cell DNA is characterized by a bimodal pattern of methylation: tissue-specific genes are methylated in most cell types whereas housekeeping genes have 5′ CpG …
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