Temporal and spatial gene expression of major bone extracellular matrix molecules during embryonic mandibular osteogenesis in rats.
作者： Jing-Xu Zhu , Yasuyuki Sasano , Ichiro Takahashi , Itaru Mizoguchi , Manabu Kagayama
关键词:
摘要: It is not known how gene expression of bone extracellular matrix molecules controlled temporally and spatially, or it related with morphological differentiation osteoblasts during embryonic osteogenesis in vivo. The present study was designed to examine expressions type I collagen, osteonectin, sialoprotein, osteopontin, osteocalcin mandibular using situ hybridization. Wistar rat embryos 13-20 days post coitum were used. condensation mesenchymal cells formed 14-day mandibles expressed genes pro-alpha 1 (I) sialoprotein osteopontin. Cuboidal surrounding the uncalcified seen as early 15-day mandibles, while flat lining surface calcified from 16-day mandibles. 1(I) osteonectin intensely but osteopontin very weakly. In contrast, strongly. Osteocytes actively, particular, demonstrated distinct pattern
springer.com
elsevier.com
sci-hub.se 参考文章(60)
Jane B. Lian, Gary S. Stein, The developmental stages of osteoblast growth and differentiation exhibit selective responses of genes to growth factors (TGF beta 1) and hormones (vitamin D and glucocorticoids). Journal of Oral Implantology. ,vol. 19, pp. 95- ,(1993)
M Silbermann, K von der Mark, An immunohistochemical study of the distribution of matrical proteins in the mandibular condyle of neonatal mice. I, Collagens Journal of Anatomy. ,vol. 170, pp. 11- 22 ,(1990)
M Noda, G A Rodan, Gene expression in osteoblastic cells Critical Reviews in Eukaryotic Gene Expression. ,vol. 1, pp. 85- 98 ,(1991)
A Oldberg, A Franzén, D Heinegård, The primary structure of a cell-binding bone sialoprotein. Journal of Biological Chemistry. ,vol. 263, pp. 19430- 19432 ,(1988) , 10.1016/S0021-9258(19)77651-0
A M Craig, J H Smith, D T Denhardt, Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. Journal of Biological Chemistry. ,vol. 264, pp. 9682- 9689 ,(1989) , 10.1016/S0021-9258(18)60584-8
S Nomura, S Hashmi, J H McVey, J Ham, M Parker, B L M Hogan, Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse sparc (osteonectin) gene. Journal of Biological Chemistry. ,vol. 264, pp. 12201- 12207 ,(1989) , 10.1016/S0021-9258(18)63841-4
A Oldberg, A Franzén, D Heinegård, M Pierschbacher, E Ruoslahti, Identification of a Bone Sialoprotein Receptor in Osteosarcoma Cells Journal of Biological Chemistry. ,vol. 263, pp. 19433- 19436 ,(1988) , 10.1016/S0021-9258(19)77652-2
G K Hunter, H A Goldberg, Modulation of crystal formation by bone phosphoproteins: role of glutamic acid-rich sequences in the nucleation of hydroxyapatite by bone sialoprotein. Biochemical Journal. ,vol. 302, pp. 175- 179 ,(1994) , 10.1042/BJ3020175
Graeme K. HUNTER, Peter V. HAUSCHKA, Robin A. POOLE, Lawrence C. ROSENBERG, Harvey A. GOLDBERG, Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins. Biochemical Journal. ,vol. 317, pp. 59- 64 ,(1996) , 10.1042/BJ3170059
Stephen Weiner, Wolfie Traub, Bone structure: from angstroms to microns. The FASEB Journal. ,vol. 6, pp. 879- 885 ,(1992) , 10.1096/FASEBJ.6.3.1740237