Auditory Processing across the Sleep-Wake Cycle: Simultaneous EEG and fMRI Monitoring in Humans

摘要: We combined fMRI and EEG recording to study the neurophysiological responses associated with auditory stimulation across sleep-wake cycle. found that presentation of stimuli produces bilateral activation in cortex, thalamus, caudate during both wakefulness nonrapid eye movement (NREM) sleep. However, left parietal and, bilaterally, prefrontal cingulate cortices thalamus were less activated NREM sleep compared wakefulness. These areas may play a role further processing sensory information required achieve conscious perception Finally, sleep, amygdala cortex more by having special affective significance than neutral stimuli. data suggests sleeping brain can process detect meaningful events.