Hemodynamic Effects of Multiple Overlapping Uncovered Stents on Aortic Dissection: Surgical Strategies and Implications for False Lumen Thrombosis

摘要: Multiple overlapping uncovered stents (MOUS) are employed to promote false lumen thrombosis in the aortic dissections (AD), when tears close vicinity branch vessels. However, overall rate of remains unsatisfactory. This study was performed investigate hemodynamic influence MOUS on dissection shed some light mechanism post-stenting thrombosis. An anatomically accurate computational fluid dynamics model developed hemodynamics AD. A parametric carried out demonstrate various post-surgery scenarios featuring representative surgical strategies involving MOUS. The use reduced-porosity slowed blood flow and decreased wall shear stress. depressed enlarged true lumen, without significantly altering outflow distribution among Compared with MOUS-alone stent graft-alone scenarios, combination graft generated a substantially large region stagnant flow. active confined an area covered by MOUS, which perfuse right renal artery lumen. helps generate favored environment for thrombus formation Application along grafts may represent more effective treatment AD than utilizing or alone.