Biologia do cancro do pulmão: conceitos actuais

作者: Renato Sotto-Mayor

DOI: 10.1016/S0873-2159(15)30798-4

关键词:

摘要: RESUMO No presente artigo de revisao o autor relata os conhecimentos actuais sobre a biologia celular e molecular do cancro pulmao, relacionandoos, sempre que possivel, com as respectivas implicacoes diagnosticas, prognosticas terapeuticas. REV PORT PNEUMOL 2002; VIII (6): 655-679

参考文章(106)
Fishback N, Przygodzki Rm, Guinee Dg, Bakker A, Finkelstein Sd, Koss M, Travis Wd, Swalsky Pa, Langer Jc, Analysis of p53, K-ras-2, and C-raf-1 in pulmonary neuroendocrine tumors. Correlation with histological subtype and clinical outcome. American Journal of Pathology. ,vol. 148, pp. 1531- 1541 ,(1996)
R. A. Kratzke, F. J. Kaye, Young Whan Kim, A. Coxon, G. A. Otterson, Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB. Oncogene. ,vol. 9, pp. 3375- 3378 ,(1994)
D P Carbone, The biology of lung cancer. Seminars in Oncology. ,vol. 24, pp. 388- 401 ,(1997)
Hong Ji Xu, Adel K. El-Naggar, William F. Benedict, Shi Xue Hu, Philip T. Cagle, Differential retinoblastoma protein expression in neuroendocrine tumors of the lung. Potential diagnostic implications. American Journal of Pathology. ,vol. 150, pp. 393- 400 ,(1997)
Y Shimosato, J Yokota, T Sugimura, M Wada, T Terasaki, Y K Fung, W F Benedict, Y Namba, T Akiyama, M Hanaoka, Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung. Oncogene. ,vol. 3, pp. 471- 475 ,(1988)
Michael J. Seckl, Enrique Rozengurt, Theresa Higgins, Fred Widmer, [D-Arg1,D-Trp5,7,9,Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells. Cancer Research. ,vol. 57, pp. 51- 54 ,(1997)
John D Minna, R. Maneckjee, Opioids induce while nicotine suppresses apoptosis in human lung cancer cells. Cell Growth & Differentiation. ,vol. 5, pp. 1033- 1040 ,(1994)
Adi F. Gazdar, Arvind K. Virmani, Yosuke Kishimoto, Jaclyn Y. Hung, Kenji Sugio, K-ras Mutations Are a Relatively Late Event in the Pathogenesis of Lung Carcinomas Cancer Research. ,vol. 54, pp. 5811- 5815 ,(1994)
J S Lee, A Yoon, S K Kalapurakal, J Y Ro, J J Lee, N Tu, W N Hittelman, W K Hong, Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor. Journal of Clinical Oncology. ,vol. 13, pp. 1893- 1903 ,(1995) , 10.1200/JCO.1995.13.8.1893