作者: Sang-Won Lee , Min-Chan Park , Yong-Beom Park , Soo-Kon Lee
DOI: 10.1007/S00296-006-0253-X
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摘要: We investigated whether serum leptin levels are elevated in patients with active rheumatoid arthritis (RA) and these correlate disease activity. Fifty RA were enrolled this study, their activity was assessed using the score 28 (DAS28). The divided into two groups according to score: a high group DAS28 > 3.2 (n = 26) low = 24). Serum determined primate antibody radioimmunoassay. had significantly higher mean levels, compared those (14.2 +/- 10.9 vs. 7.0 3.4 ng/ml, P < 0.05). Mean adjusted BMI 0.6 0.5 ng m(2)/ml kg for 0.3 0.2 group, respectively, which also different (P Both correlated well (r 0.363 0.368, 0.05) CRP 0.433 0.472, 0.05), respectively. Sixteen of 26 at initial assessment re-evaluated, point decreased less than 3.2. follow-up level lower (7.8 3.7 16.1 12.7 In conclusion, activity, when controlled.