Pharmaceutical compositions and formulations of metformin extended release tablets

摘要: The present invention relates to a metformin extended release tablet, particularly tablet comprising metformin, which is effective in treating non-insulin dependent diabetes mellitus, as active ingredient, and matrix hydrophilic polymers hydrophobic materials are mixed at specific proportion. enable controlling of the pore size gel layer formed by water swelling, thereby enabling primary control drug rate. And, block pores layer, secondary Therefore, has better dissolution properties than conventional tablets and, thus, enables constant rate even with less matrix. A blood level can be maintained one administration day made smaller, makes easier production simpler.