Transplacental passage of lamotrigine in a human placental perfusion system in vitro and in maternal and cord blood in vivo
作者： Päivi K. Myllynen , Päivi K. Pienimäki , Kirsi H. Vähäkangas
DOI: 10.1007/S00228-002-0544-4
关键词:
摘要: Objective We studied transplacental passage of lamotrigine (3,5-diamino-6-[2,3-dichlorophenyl]-1,2,4-triazine; LTG) using an ex vivo human placental perfusion method and in samples.
springer.com
sci-hub.se 参考文章(32)
P. Bülau, W. D. Paar, G. E. von Unruh, Pharmacokinetics of oxcarbazepine and 10-hydroxy-carbazepine in the newborn child of an oxcarbazepine-treated mother. European Journal of Clinical Pharmacology. ,vol. 34, pp. 311- 313 ,(1988) , 10.1007/BF00540963
Philippe Bourget, Cédric Roulot, Hervé Fernandez, Models for Placental Transfer Studies of Drugs Clinical Pharmacokinectics. ,vol. 28, pp. 161- 180 ,(1995) , 10.2165/00003088-199528020-00006
P. Pienimäki, S. Fuchs, J. Isojärvi, K. Vähäkangas, Improved detection and determination of carbamazepine and oxcarbazepine and their metabolites by high-performance liquid chromatography Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 673, pp. 97- 105 ,(1995) , 10.1016/0378-4347(95)00246-F
Eija S. Lampela, Laura H. Nuutinen, Tero I. Ala-Kokko, Riitta M. Parikka, Risto S. Laitinen, Pentti I. Jouppila, Kirsi H. Vähäkangas, Placental transfer of sulindac, sulindac sulfide, and indomethacin in a human placental perfusion model American Journal of Obstetrics and Gynecology. ,vol. 180, pp. 174- 180 ,(1999) , 10.1016/S0002-9378(99)70171-7
James W. A. RITCHIE, Peter M. TAYLOR, Role of the System L permease LAT1 in amino acid and iodothyronine transport in placenta Biochemical Journal. ,vol. 356, pp. 719- 725 ,(2001) , 10.1042/BJ3560719
Torbjorn Tomson, Inger Ohman, Sigurd Vitols, Lamotrigine in Pregnancy and Lactation: A Case Report Epilepsia. ,vol. 38, pp. 1039- 1041 ,(1997) , 10.1111/J.1528-1157.1997.TB01489.X
Tove Tuntland, Aleksandrs Odinecs, Conrad M. Pereira, Connie Nosbisch, Jashvant D. Unadkat, In vitro models to predict the in vivo mechanism, rate and extent of placental transfer of dideoxynucleoside drugs against human immunodeficiency virus American Journal of Obstetrics and Gynecology. ,vol. 180, pp. 198- 206 ,(1999) , 10.1016/S0002-9378(99)70175-4
Daniela Omarini, Vanna Pistotti, Maurizio Bonati, Placental perfusion. An overview of the literature. Journal of Pharmacological and Toxicological Methods. ,vol. 28, pp. 61- 66 ,(1992) , 10.1016/1056-8719(92)90048-6
T. A. Tran, I. E. Leppik, K. Blesi, S. T. Sathanandan, R. Remmel, Lamotrigine clearance during pregnancy Neurology. ,vol. 59, pp. 251- 255 ,(2002) , 10.1212/WNL.59.2.251
Kenneth L Audus, Controlling drug delivery across the placenta. European Journal of Pharmaceutical Sciences. ,vol. 8, pp. 161- 165 ,(1999) , 10.1016/S0928-0987(99)00031-7