Effect of fumonisin B1 on lymphatic organs in broiler chickens - pathomorphology
作者： Elena Georgieva Gardeva , Reneta Aleksandrova Toshkova , Russy Vladimirov Russev , Metody Hristov Petrichev , Anton Ivanov Kril
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摘要: The purpose of this study was to establish the path omorphological alterations in lymphatic organs broiler chickens fed forages containing fumonisin B1 (FB1), known cause immunodeficiency. birds were treated wit h mycotoxin isolated from corn contaminated with F. verticilloides (moniliforme). Apoptotic and necrotic changes recorded under light electron microscopes. Significant morphological such as focal necrosis an increased number a poptotic lymphocytes epithelial cells found mainly thymus d spleen, while bursa Fabricii less affected. It can be concluded that FB1 causes vivo suppression development, differentiation, f unction lymphoid stromal epith elial reticular cells, activates processes leading cell death immune system chickens.
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