Secular trends of chickenpox among military population in Israel in relation to introduction of varicella zoster vaccine 1979-2010.

摘要: Chickenpox is a contagious disease caused by the varicella zoster virus. There scarce data on long-term trends of chickenpox and its relation to vaccinations practices. We aimed evaluate in military population during period 1979–2010 assess temporal associations with introduction vaccine civilian Israel 2000. The archives Epidemiology Section Defense Forces, where notifiable disease, were reviewed for all cases from January 1, 1979–December 31, 2010. Annual monthly incidence rates calculated analyzed introduction. Between 1979–2000, fluctuated around 10 per 10,000 soldiers without clear trend. Since 2000 there has been dramatic 10-fold decline incidence, especially notable since 2008, eight lowest rate ever recorded, 2009, 0.57 soldiers. A seasonal sinusoidal pattern was clearly demonstrated, rising November May followed gradual October. results this study suggest that have significantly declined almost disappeared completely 2008 as included state-funded routine childhood immunization schedule. These findings underscore need strong surveillance system will aid determing vaccination policies.