Biomimetic collagen/apatite coating formation on Ti6Al4V substrates.
作者： Zengmin Xia , Xiaohua Yu , Mei Wei
DOI: 10.1002/JBM.B.31970
关键词:
摘要: Hydroxyapatite and type I collagen are two major components of natural bone. They have been used extensively to engineer biomaterial surfaces for enhanced implant-bone integrations. In this study, a collagen/apatite composite coating was successfully deposited on treated Ti6Al4V by coprecipitation apatite in collagen-containing modified simulated body fluid (m-SBF). X-ray diffraction Fourier-transform infrared spectroscopy results indicated that the achieved bone-like carbonated I, which is similar composition The morphology could be tailored carefully adjusting concentration m-SBF. addition, both thickness bonding strength were down regulated Collagen inhibited nucleation metallic substrate, thereby reduced coating. an vitro cell culture study conducted collagen-apatite surfaces. Addition promoted osteoblast activities, may lead early bone formation.
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