Relationship between posttraumatic stress disorder and type 2 diabetes in a population-based cross-sectional study with 2970 participants.

摘要: Abstract Objectives To evaluate the association of posttraumatic stress disorder (PTSD) with type 2 diabetes (T2D) or prediabetes in a large population-based sample. Methods In 2970 subjects (aged 32–81 years) drawn from cross-sectional study KORA F4 Augsburg region (Southern Germany) PTSD screening was performed employing Posttraumatic Diagnostic Scale, Impact Event and interview data. The exposure variable sub-classified into partial full additionally traumatic event but no PTSD” to “The classified (1) (2) event, PTSD, (3) (4) PTSD. A total 50 (1.7%) qualified for whereas 261 (8.8%) 333 (11.2%) suffered T2D 498 (16.8%) as assessed by an oral glucose tolerance test physicians’ validation. associations were estimated multinomial logistic regression analyses adjustments sociodemographic characteristics, metabolic risk factors psychopathological conditions. Results model adjusted characteristics factors, significantly associated (OR: 3.90, 95% CI: 1.61–9.45, p  = 0.003) compared event. Significance remained after additional adjustment other conditions 3.56, 1.43–8.85,  = 0.006). Regarding prediabetes, significant observed. Conclusions Suffering might activate chronic symptoms trigger physiological mechanisms leading T2D. Prospective studies are needed investigate temporal causal relationships between