Endogenous Antioxidants and Radical Scavengers
作者： Angela Maria Rizzo , Patrizia Berselli , Stefania Zava , Gigliola Montorfano , Manuela Negroni
DOI: 10.1007/978-1-4419-7347-4_5
关键词:
摘要: All living organisms are constantly exposed to oxidant agents deriving from both endogenous and exogenous sources capable modify biomolecules induce damages. Free radicals generated by oxidative stress exert an important role in the development of tissue damage aging. Reactive species (RS) derived oxygen (ROS) nitrogen (RNS) pertain free family constituted various forms activated or nitrogen. RS continuosly produced during normal physiological events but can be removed antioxidant defence mechanism: imbalance between mechanism leads modifications cellular membrane intracellular molecules. In this chapter only molecules will critically discussed, such as Glutathione, Alpha-lipoic acid, Coenzyme Q, Ferritin, Uric Bilirubin, Metallothioneine, L-carnitine Melatonin.
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Hakan Gullu, Dogan Erdogan, Derya Tok, Semra Topcu, Mustafa Caliskan, Taner Ulus, Haldun Muderrisoglu, High Serum Bilirubin Concentrations Preserve Coronary Flow Reserve and Coronary Microvascular Functions Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 25, pp. 2289- 2294 ,(2005) , 10.1161/01.ATV.0000185806.61430.7C
Graziano Riccioni, Tonino Bucciarelli, Barbara Mancini, Carmine Di Ilio, Valerie Capra, Nicolantonio D’Orazio, The role of the antioxidant vitamin supplementation in the prevention of cardiovascular diseases Expert Opinion on Investigational Drugs. ,vol. 16, pp. 25- 32 ,(2007) , 10.1517/13543784.16.1.25
Da Hong Wang, Keiki Ogino, Biomarkers of oxidative/nitrosative stress: an approach to disease prevention. Acta Medica Okayama. ,vol. 61, pp. 181- 189 ,(2007) , 10.18926/AMO/32871
A. Nunomura, P. Moreira, A. Takeda, M. Smith, G. Perry, Oxidative RNA damage and neurodegeneration Current Medicinal Chemistry. ,vol. 14, pp. 2968- 2975 ,(2007) , 10.2174/092986707782794078
Sophie Lanone, Sébastien Bloc, Roberta Foresti, Abdelhamid Almolki, Camille Taillé, Jacques Callebert, Marc Conti, Delphine Goven, Michel Aubier, Bertrand Dureuil, Jamel El‐Benna, Roberto Mottierlini, Jorge Boczkowski, Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats. The FASEB Journal. ,vol. 19, pp. 1890- 1892 ,(2005) , 10.1096/FJ.04-2368FJE
V Srinivasan, SR Pandi-Perumal, DP Cardinali, B Poeggeler, R Hardeland, Melatonin in Alzheimer's disease and other neurodegenerative disorders. Behavioral and Brain Functions. ,vol. 2, pp. 15- 15 ,(2006) , 10.1186/1744-9081-2-15
Mustafa Buyukavci, Oner Ozdemir, Steven Buck, Mark Stout, Yaddanapudi Ravindranath, Sureyya Savasan, Melatonin cytotoxicity in human leukemia cells: relation with its pro‐oxidant effect Fundamental & Clinical Pharmacology. ,vol. 20, pp. 73- 79 ,(2006) , 10.1111/J.1472-8206.2005.00389.X
K. Richard Bruckdorfer, Antioxidants and CVD Nutrition Society Annual Conference. Symposium 'Diet and cancer', Symposium 'Diet and bone health', Symposium 'Diet and CVD', Symposium 'Diet and mental health'. ,vol. 67, pp. 214- 222 ,(2008) , 10.1017/S0029665108007052
Paul N. Hopkins, Lily L. Wu, Steven C. Hunt, Brent C. James, G. Michael Vincent, Roger R. Williams, Higher serum bilirubin is associated with decreased risk for early familial coronary artery disease Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 16, pp. 250- 255 ,(1996) , 10.1161/01.ATV.16.2.250
Masuko Ushio-Fukai, Kathy K. Griendling, Dan Sorescu, NAD(P)H Oxidase: Role in Cardiovascular Biology and Disease Circulation Research. ,vol. 86, pp. 494- 501 ,(2000) , 10.1161/01.RES.86.5.494