Carpentier-Edwards standard porcine bioprosthesis: primary tissue failure (structural valve deterioration) by age groups.

作者: W.R.E. Jamieson , L.J. Rosado , A.I. Munro , A.N. Gerein , L.H. Burr

DOI: 10.1016/S0003-4975(10)65888-2

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摘要: Abstract Primary tissue failure (structural valve deterioration) has been documented as the most prominent complication of porcine bioprostheses. The influence age on primary received limited consideration. From 1975 to 1986, 1,301 Carpentier-Edwards standard bioprostheses were implanted in 1,183 patients 1,201 operations. Of total number prostheses, 97.7% prior 1983. mean follow-up was 5.6 years and 97.5% complete. identified 96 (98 operations) at reoperation (95) or autopsy (3). One hundred four (104) prostheses involved. Thirty-one failed after aortic replacement (AVR), 49 mitral (MVR), 24 multiple-valve (18 patients). There 47 male female patients. implantation (range, 8 72 years). time 74.0 months. freedom from 10 is 77.0 ± 2.9% overall; for AVR, 83.1 3.7%; MVR, 72.1 4.9%; replacement, 65.5 7.8%. deterioration less than 20 significantly that other groups. increased by decades; greatest noted 70 80 old older. 30 26.8 17.2%; 59 years, 77.4 3.0%; 60 older, 4.2%. prosthesis performed superiorly younger older groups while intermediate group there no difference performance prostheses.

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