Endothelin-A Receptor Antagonist–Mediated Vasodilatation Is Attenuated by Inhibition of Nitric Oxide Synthesis and by Endothelin-B Receptor Blockade

作者: Marianne C. Verhaar , Fiona E. Strachan , David E. Newby , Nicholas L. Cruden , Hein A. Koomans

DOI: 10.1161/01.CIR.97.8.752

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摘要: Background—The role of endothelin (ET)-1 in maintenance of basal vascular tone has been demonstrated by local and systemic vasodilatation to endothelin receptor antagonists in …

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