T Cells Can Be Activated by Peptides That Are Unrelated in Sequence to Their Selecting Peptide
作者： Leszek Ignatowicz , William Rees , Rafal Pacholczyk , Hanna Ignatowicz , Elenora Kushnir
DOI: 10.1016/S1074-7613(00)80521-X
关键词:
摘要: We tested the ability of CD4+ T cells, selected in thymus by reaction with class II protein bound to a single peptide, react same other peptides. The cells reacted all peptides tested, including one that was quite unlike selecting peptide cell receptor binding residues. receptors on II/peptide-reactive from II/single mice were similar but not identical some those normal animals. Thus, selects subset is related many
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