Critical flicker fusion in primary degenerative dementia of the alzheimer’s type (PDDAT): Clinical implications (II)

摘要: Critical Flicker Fusion Threshold (CFFT) and the difference between fusion flicker thresholds were examined in 23 female three male patients with Primary Degenerative Dementia of Alzheimer’s type (PDDAT). The control group consisted age, sex, occupational class-matched, normal volunteers. Patients had a mean age 81.7 years ±6.05 (range 67–89); diagnosis was based on DSM-IIIR criteria. psychophysical method limits used to measure ascending (fusion) descending (flicker) means average being CFFT. Both CFFT able distinguish volunteers at high level statistical significance (t=2.054, df=50, p<0.0018 t=−4.903, p<0.0000 respectively). Sixty-five percent scores below 1.96 SD volunteer 85 mean. not significantly different two groups but greater than (t=5.617, df=25, p<0.0000). One interpretation results that PDDAT have significant reduction sensitivity Central Nervous System suprathreshold flicker. Accurate early (probable disease) continues remain one most difficult areas dementia research. use simple quantitative measures such as may an important role play overall assessment PDDAT.