Electromagnetic information delivery as a new tool in translational medicine.

作者: Foletti Alberto , Ledda Mario , Lisi Antonella , Grimaldi Settimio , Piccirillo Sara

DOI:

关键词:

摘要: Some experimental evidences of the procedure defined as electro-magnetic information delivery, mediated through aqueous system, have accumulated in last two decades. The present work is based on hypotheses that an system like those enfolded livings, could play additional synergic role modulating biological functions. Aqueous generate dissipative structures under appropriate patterns electromagnetic signals providing basis for storing and retrieving biologic activities. External stimuli resonant conditions with some coherent domains water can induce dipole moments re-patterning a way these structure start to oscillate coherently each other generating new phase correlation. This allows external stimulus be stored, translated transferred by systems target, driving selectively their endogenous activity mimicking effect specific source molecule. Signals from chemical differentiation agent such Retinoic Acid (RA) was captured target culture medium Neuroblastoma Cell Line (LAN-5) proliferation rate assessed, order investigate cell responses system.

参考文章(24)
June L. Biedler, Motoi Hanada, Stanislaw Krajewski, Robert A. Ross, Barbara A. Spengler, John C. Reed, Shigeki Tanaka, Dominique Cazals-Hatem, Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells. Cancer Research. ,vol. 53, pp. 4978- 4986 ,(1993)
Antonella Casalaro, Marina Lanciotti, Paolo Cornaglia-Ferraris, Mirco Ponzoni, Paolo Giuseppe Montaldo, The combination of γ-interferon and tumor necrosis factor causes a rapid and extensive differentiation of human neuroblastoma cells Cancer Research. ,vol. 52, pp. 931- 939 ,(1992)
Nadia Marchettini, Emilio Del Giudice, Vladimir Voeikov, Enzo Tiezzi, Water: A medium where dissipative structures are produced by a coherent dynamics Journal of Theoretical Biology. ,vol. 265, pp. 511- 516 ,(2010) , 10.1016/J.JTBI.2010.05.021
Y. Thomas, M. Schiff, L. Belkadi, P. Jurgens, L. Kahhak, J. Benveniste, Activation of human neutrophils by electronically transmitted phorbol–myristate acetate Medical Hypotheses. ,vol. 54, pp. 33- 39 ,(2000) , 10.1054/MEHY.1999.0891
Emilio Del Giudice, Alberto Tedeschi, Water and autocatalysis in living matter. Electromagnetic Biology and Medicine. ,vol. 28, pp. 46- 52 ,(2009) , 10.1080/15368370802708728
Albert Szent-Györgyi, Biology and Pathology of Water Perspectives in Biology and Medicine. ,vol. 14, pp. 239- 249 ,(1971) , 10.1353/PBM.1971.0014
E Abemayor, N Sidell, Human neuroblastoma cell lines as models for the in vitro study of neoplastic and neuronal cell differentiation. Environmental Health Perspectives. ,vol. 80, pp. 3- 15 ,(1989) , 10.1289/EHP.89803
Mauro Piacentini, Margherita Annicchiarico-Petruzzelli, Serafina Oliverio, Lucia Piredda, June L. Biedler, Gennaro Melino, Phenotype‐specific “tissue” transglutaminase regulation in human neuroblastoma cells in response to retinoic acid: Correlation with cell death by apoptosis International Journal of Cancer. ,vol. 52, pp. 271- 278 ,(1992) , 10.1002/IJC.2910520220