Exacerbations of COPD diagnosed in primary care: changes in spirometry and relationship to symptoms.

摘要: The study objective was to assess spirometric changes during resolution of acute exacerbations COPD diagnosed and treated in primary care their relationship clinical features. Spirometry carried out on 101 patients with AECOPD presenting a physician the day presentation, days 5, 10–14, 28, 56 after presentation traces were analyzed including quality reproducibility. Eighty-three produced at least one technically acceptable spirometer trace 60 all time points. increase FEV1 VC occurred first 5 median postbronchodilator 55 ml (IQR, −63 128, p = 0.003) 90 (IQR −78 308 ml, < 0.001). improvement prebronchodilator values related bronchodilator reversibility strongest for (by 28: r 0.522, Patients purulent sputum demonstrated impro...