Column-switching HPLC for the analysis of plasma in PET imaging studies.

作者: John Hilton , Fuji Yokoi , Robert F Dannals , Hayden T Ravert , Zsolt Szabo

DOI: 10.1016/S0969-8051(00)00125-6

关键词:

摘要: A column-switch high performance liquid chromatography method for the analysis of 4 mL plasma is described with six examples [(11)C]-labeled positron-emission tomography imaging agents. Complete extraction all but most polar metabolites by reverse phase capture column achieved disruption protein binding 8 M urea.

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