The effect of concomitant fibromyalgia in HIV infected patients receiving antiretroviral therapy: a prospective cross-sectional study.

摘要: HIV infected patients receiving antiretroviral therapy (ART) have extensive musculoskeletal system involvement. Arthralgia and myalgia are the most common forms. Fibromyalgia Syndrome (FMS) is a chronic pain syndrome of characterized by diffuse including arthralgia myalgia. These overlapping symptoms suggested relationship between FMS. The primary purpose this study was to determine prevalence FMS in HIV/AIDS patients. secondary objective investigate effects on functional status, depression, fatigue, sleep pattern quality life. A total 225 who were ART included cross-sectional prospective study. demographic data participants, CD4 T-lymphocyte count (cells/mm3), viral load (> 40 copy/ml), regimens recorded. diagnosis based 2016 revision diagnostic criteria. All completed following questionnaires: Fibromyalgia Impact Questionnaire (FIQ), Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale (FSS), SF-36 scale. found 20% (n = 45). mean duration disease 4.74 ± 4.42 years; it significantly longer with (p = 0.007). median be 616.00 ± 303.91 cells/mm3, higher without (p = 0.06). No statistically significant difference two groups according drug used. FIQ, BDI, PSQI, FSS all subgroups scale (p = 0.001). slightly frequency determined compared previous studies. It shown that presence negatively affected function, sleep, Detection may decrease disorders increase life should distinguished correctly for an accurate treatment management increasing compliance.