Single-cell activity and synchronous bursting in the rat hippocampus during waking behavior and sleep

摘要: Abstract Eighty-one of eighty-five isolated neurons recorded from the rat dorsal hippocampus (Ammon's horn and area dentata) were classifiable into four types according to their firing patterns behavioral correlates. Sixty-two percent total complex spike cells which fired slowly ( 2 s ) most time, but active during slow-wave sleep, slightly less awake immobility, least movement paradoxical sleep. Theta (21% total) generally much faster than increased discharge rate whenever rhythmical slow activity was present in hippocampal EEG (i.e., sleep). The correlates seven putative granule similar those theta cells. However, behavior-dependent changes frequency more pronounced former latter. Three (fast) observed any other cell all states showed cells, fast found both Ammon's dentate hilus. A type multiunit burst pyramidal layer. It occurred frequently virtually absent considered represent a summed synchronously bursting Possible cellular mechanisms state-dependent activities different neuronal populations are discussed.