Chlorin and bacteriochlorin-based difunctional aminophenyl DTPA and N2S2 conjugates

摘要: A compound comprising a chemical combination of photodynamic tetra-pyrrolic compound with plurality radionuclide element atoms such that the may be used to enhance MR imaging and also be used as for use in photodynamic therapy treat hyperproliferativc tissue. The preferred compounds have the structural formula : where R 1 , 2 2a 3 3a 4 5 5a 6 7 7a 8 cumulatively contain at least two functional groups will complex or combine an enhancing or ion. is intended include complexes combinations includes the treatment tumors and other hyperproliferative