Signatures of clinical outcome in gastro intestinal stromal tumors and method of treatment of gastroinstestinal stromal tumors

作者: Frédéric Chibon , Jean-Michel Coindre , Alain Aurias

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摘要: The present invention refers to a method for in vitro predicting survival and/or metastatic outcome of gastrointestinal stromal tumors (GISTs), characterized that it comprises the measure level, patient-derived biological sample GIST, pool polypeptides or polynucleotides consisting Aurora kinase A (AURKA) and kit prediction patient suffering from development metastases treated efficacy treatment means detecting quantify, sample, AURKA expression calculation GI. also screening compounds use GISTs an inhibitor its GISTs.

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