The neurophysiological basis and the role of inflammatory reactions in dentine hypersensitivity.

摘要: Abstract Recent studies indicate that intradental A-type nerve fibres are responsible for the sensitivity of dentine and activated by fluid movements in dentinal tubules (hydrodynamic mechanism). The patency affects to a great extent. Both Aδ- Aβ-type respond (hydrodynamic) stimulation similar way. Only few have been made on regional or receptive areas fibres. results innervating different parts coronal equally sensitive but those cervical area may be less responsive. Inflammation pulp can considerably alter sensitivity. In dog teeth with chronically exposed dentine, responses hydrodynamic were reduced although other functional changes indicated sensitization. This due spontaneously occurring block tubules. acute experiments cat open tubules, certain inflammatory mediators increase responding It seems C-fibres do not dentine. They polymodal when external stimuli reach proper. could perhaps mediate dull pain connected pulpitis. However, they might also an important modifying effect because release neuropeptides, which function reactions.